کنگره بین المللی رویکردهای نوین سبک زندگی، پیشگیری و درمان سرطان

صفحه اصلی / اولین کنگره بین المللی رویکردهای نوین سبک زندگی، پیشگیری و درمان سرطان

Dietary patterns in relation to risk of colorectal cancer: a case control study

نویسندگان :

Fariba Zare (دانشگاه علوم پزشکی ایران) , Shima Ataee (دانشکده علوم پزشکی بهبهان) , Nima Daneshi (دانشگاه علوم پزشکی ایران)

کلمات کلیدی :

colorectal cancer،food frequency questionnaire،dietary patterns

چکیده :

Colorectal cancer (CRC) is the fourth leading cause of cancer mortality in both men and women. In Iran, CRC is the fourth and third most commonly diagnosed malignancy in men and women, respectively. The relationship between major dietary patterns and colorectal cancer (CRC) in other populations largely remains consistent across studies. Methods We conducted a hospital case-control study among Iranian adults referred to hospitals in Ahvaz. Data was collected from 150 colorectal cancer patients and 150 controls with non-neoplastic conditions. Dietary data were evaluated by food frequency questionnaire. Logistic regression analyses were performed to investigate the association between dietary patterns and the CRC risk. Results Three major dietary patterns were derived using factor analysis, namely a healthy, western and traditional pattern. Results suggest that the Westernized pattern increased the risk of CRC (OR=2.4, 95% CI=1.77-2.93). on the other hand, the Healthy dietary pattern was associated with a decreased risk of Colorectal Cancer (OR=0.36, 95% CI=0.28-0.51). Also our study not shown any significant association between traditional pattern and the Colorectal Cancer (OR=0.87, 95% CI=0.49-1.47). Conclusion Our study suggested that the “Healthy dietary pattern" seems reduce the risk of CRC, while the “Western dietary pattern" was associated with increased risk of CRC. In addition, the diet-disease relationships investigated here could be used to develop targeted interventions aimed at promoting healthy eating habits, with the goal of preventing CRC.

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