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صفحه اصلی
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اولین کنگره بین المللی رویکردهای نوین سبک زندگی، پیشگیری و درمان سرطان
Unveiling the Potential of Medical Nanotechnology in Early Cancer Detection: A Frontier in Oncology Diagnostics
نویسندگان :
Sonia Fathi (دانشگاه علوم پزشکی خراسان شمالی) , Reza Maleki baladi (دانشگاه آزاد اسلامی واحد بجنورد)
کلمات کلیدی :
Medical nanotechnology،Early cancer detection،Oncology diagnostics،Fluorescent nanoparticles،Molecular imaging
چکیده :
Introduction: The application of nanotechnology in oncology diagnostics, specifically for early detection of cancer, marks a major frontier in medical research. This review article aims to explore the promising potential of using nanotechnology as a refined tool for detecting cancer in its early stages. This approach seeks to leverage the unique properties of nanoparticles, such as their reactive nature and high surface-to-volume ratio, to enhance the precision and efficiency of oncology diagnostics. Methods: An in-depth review and critical analysis were undertaken to understand the role of nanotechnology in medical diagnostics, focusing on the utilization of fluorescent nanoparticles for Molecular Imaging (MI). Considerations were given to a range of existing studies detailing advanced diagnostics methods and their application in early detection, response monitoring, and in vivo visualization of living cells. Additionally, thorough attention was paid to the synthesizing methods of these nanoparticles and their prospective application in clinical theranostics. Results: Encouraging findings revealed that the application of nanotechnology in fluorescence imaging and Magnetic Resonance Imaging (MRI) could potentially result in earlier and more accurate diagnosis of cancer than conventional imaging methods. The distinct capabilities of nanoparticles for targeted drug delivery and gene treatment proved particularly promising. Furthermore, it was found that fluorescent nanoparticles - including quantum dots (QDs), upconversion, and dyedoped nanoparticles - played a significant role in optical MI. Multifunctional nanoparticles were determined to be effective theranostic agents, useful for diagnosis and therapy simultaneously. Conclusion: The potential for medical nanotechnology in early cancer detection is vast and offers a compelling pathway for advancements in oncology diagnostics. Notwithstanding its promising attributes, comprehensive studies and clinical trials are warranted to validate the safe and efficient application of nanotechnology in clinical settings. By focusing on fluorescent nanoparticles, the research presents a promising avenue for more timely and precise cancer detection, thus leading to effective treatment planning. This investigation assertively supports the continued exploration and development of nanotechnology as a diagnostic method, paving the way for unprecedented innovation in oncology diagnostics.
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