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صفحه اصلی
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اولین کنگره بین المللی رویکردهای نوین سبک زندگی، پیشگیری و درمان سرطان
The role of Negative pressure wound therapy in wound treatment of cancer patients
نویسندگان :
Hamed Savadkoohi (دانشگاه علوم پزشکی شهید بهشتی)
کلمات کلیدی :
nursing،cancer،NPWT،management
چکیده :
Background: Negative pressure wound therapy (NPWT) has increasingly been a part of the plastic surgeons because it reduces edema, improves angiogenesis, and promotes granulation formation in a variety of settings. Historically, an absolute contraindication to the use of NPWT is active malignancy due to theoretical risks of increased tumorigenesis, cancer spread, and hemorrhage. However, few studies have evaluated the effects of NPWT on malignant wounds. In contrast, there is evidence that NPWT is beneficial for palliation in malignancy.NPWT use in malignancy has been described as a palliative wound dressing and as temporary coverage before definitive closure. Compared with conventional wound care, NPWT may facilitate improved pain control and a reduction in drainage and malodor.NPWT has also shown to be beneficial in reducing the size of malignant wounds, allowing for eventual closure. This has similarly been demonstrated in radiated metastatic wounds. several previous studies have demonstrated that NPWT may be of benefit in malignancy settings when used with a palliative intent. In patients at the end of life, measures that reduce pain, malodor, drainage of wounds, and limit trips to the operating room may improve quality of life. Further, although studies are limited and are not necessarily assessing for this, NPWT application to malignant wounds has not been shown to stimulate tumorigenesis or hemorrhage. The use of NPWT for malignant wounds may have utility as a palliative therapeutic intervention to reduce complications associated with the wounds and to increase patient comfort. Dedicated studies are necessary to further evaluate the safety and efficacy of NPWT in malignancy. Materials and Methods: In this systematic review and meta-analysis study, four online databases (PubMed, Scopus, web of Science, ProQuest) from related articles from 2017-2022 were searched for related keywords. The quality of articles was evaluated using the Newcastle-Ottawa (NOS) criterion. This study, comprising a systematic review and meta‐analysis, was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement Results: This systematic review and meta‐analysis study summarised the available evidence on the effects associated with the application of NPWT for malignant wounds. Conclusions: NPWT is a safe method for accelerating healing and lowering the infection rate of burn wounds. Its use in burn wound and chronic wounds treatment is recommended provided it is applied under appropriate circumstances. further large‐scale RCTs are required to provide more evidence of its effectiveness for treating malignant wounds.We consider that, in malignant patients, it can present a key point to accelerate the healing process and stop in end of life patiemt with cancer. Legal entity responsible for the study:The author Funding:Has not received any funding Disclosure:All authors have declared no conflicts of interest
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